Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 4/20 | 0.52 |
| ▸ | CD40LG | P29965 | 4/20 | 0.52 |
| ▸ | FGF1 | P05230 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 3/20 | 0.45 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341705 | 0.93 | FGF1 (0.56) | CD40CD40LGFGF1CCR8TIMP3 | |
| SCHEMBL10907632 | 0.88 | KMT2A (0.52) | CD40CD40LGCCR8TIMP3NPC1 | |
| SCHEMBL11426641 | 0.86 | CASP6 (0.46) | CD40CD40LGFGF1CCR8NPC1 | |
| SCHEMBL10907563 | 0.86 | CD40 (0.50) | CD40CD40LGFGF1CCR8TIMP3 | |
| SCHEMBL10908939 | 0.85 | CD40 (0.52) | CD40CD40LGFGF1CCR8TIMP3 | |
| SCHEMBL10909141 | 0.83 | CD40 (0.52) | CD40CD40LGFGF1CCR8TIMP3 | |
| SCHEMBL10907794 | 0.83 | HPSE (0.44) | CD40CD40LGCCR8TIMP3NPC1 | |
| SCHEMBL11434698 | 0.82 | CD40 (0.66) | CD40CD40LGNPC1RAB9APARP1 | |
| SCHEMBL10907711 | 0.82 | TIMP3 (0.52) | CD40CD40LGFGF1CCR8TIMP3 | |
| SCHEMBL10908252 | 0.82 | CD40 (0.57) | CD40CD40LGFGF1TIMP3CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |