Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 5/20 | 0.53 |
| ▸ | CD40 | P25942 | 1/20 | 0.52 |
| ▸ | CD40LG | P29965 | 1/20 | 0.52 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | FGF1 | P05230 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905173 | 0.95 | TIMP3 (0.53) | TIMP3CD40CD40LGCCR8TRPV1 | |
| SCHEMBL11335401 | 0.93 | TIMP3 (0.61) | TIMP3CD40CD40LGCCR8TRPV1 | |
| SCHEMBL11347634 | 0.88 | TIMP3 (0.61) | TIMP3CD40CD40LGCCR8TRPV1 | |
| SCHEMBL10907805 | 0.87 | KMT2A (0.56) | TIMP3CD40CD40LGCCR8TRPV1 | |
| SCHEMBL11427658 | 0.86 | CASP6 (0.48) | TIMP3CD40CD40LGCCR8TRPV1 | |
| SCHEMBL10909738 | 0.85 | MEN1 (0.47) | TIMP3CD40CD40LGTRPV1MEN1 | |
| SCHEMBL10909181 | 0.84 | CD40 (0.48) | TIMP3CD40CD40LGCCR8TRPV1 | |
| SCHEMBL10908534 | 0.83 | MAOB (0.40) | TIMP3CD40CD40LGCCR8MEN1 | |
| SCHEMBL11431130 | 0.82 | CD40 (0.66) | TIMP3CD40CD40LGMEN1KMT2A | |
| SCHEMBL10909124 | 0.82 | KMT2A (0.56) | TIMP3CD40CD40LGCCR8TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |