Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 4/20 | 0.48 |
| ▸ | CD40LG | P29965 | 4/20 | 0.48 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.47 |
| ▸ | FGF1 | P05230 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351833 | 0.93 | TIMP3 (0.55) | CD40CD40LGTIMP3FGF1KMT2A | |
| SCHEMBL10908808 | 0.86 | CD40 (0.48) | CD40CD40LGTIMP3FGF1KMT2A | |
| SCHEMBL10907679 | 0.84 | TIMP3 (0.53) | CD40CD40LGTIMP3FGF1KMT2A | |
| SCHEMBL10907563 | 0.83 | CD40 (0.50) | CD40CD40LGTIMP3FGF1KMT2A | |
| SCHEMBL10996673 | 0.83 | TIMP3 (0.46) | CD40CD40LGTIMP3FGF1KMT2A | |
| SCHEMBL10908939 | 0.82 | CD40 (0.52) | CD40CD40LGTIMP3FGF1KMT2A | |
| SCHEMBL10907664 | 0.80 | CD40 (0.50) | CD40CD40LGTIMP3FGF1KMT2A | |
| SCHEMBL10907602 | 0.80 | CD40 (0.52) | CD40CD40LGTIMP3FGF1CCR8 | |
| SCHEMBL10905173 | 0.80 | TIMP3 (0.53) | CD40CD40LGTIMP3FGF1KMT2A | |
| SCHEMBL10908823 | 0.79 | TIMP3 (0.52) | CD40CD40LGTIMP3FGF1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |