Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.51 |
| ▸ | TIMP3 | P35625 | 3/20 | 0.49 |
| ▸ | CASP6 | P55212 | 2/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | FGF1 | P05230 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11350067 | 0.93 | TIMP3 (0.57) | ENPP2TIMP3CASP6CTDSP1APEX1 | |
| SCHEMBL10905294 | 0.91 | CASP6 (0.55) | ENPP2TIMP3CASP6CTDSP1APEX1 | |
| SCHEMBL10908211 | 0.87 | MEN1 (0.53) | ENPP2TIMP3CASP6CTDSP1APEX1 | |
| SCHEMBL11427680 | 0.87 | CASP6 (0.59) | ENPP2TIMP3CASP6CTDSP1APEX1 | |
| SCHEMBL10909117 | 0.84 | MEN1 (0.46) | ENPP2TIMP3CASP6CTDSP1APEX1 | |
| SCHEMBL11352224 | 0.83 | PRMT1 (0.57) | ENPP2TIMP3CASP6CTDSP1APEX1 | |
| SCHEMBL10907786 | 0.83 | NT5E (0.44) | ENPP2TIMP3CASP6CTDSP1APEX1 | |
| SCHEMBL10909144 | 0.83 | ENPP2 (0.56) | ENPP2TIMP3CASP6CTDSP1TRPV1 | |
| SCHEMBL11436268 | 0.83 | MAPT (0.57) | ENPP2APEX1TRPV1CA2CA1 | |
| SCHEMBL10907420 | 0.81 | CASP6 (0.52) | ENPP2TIMP3CASP6CTDSP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |