Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.55 |
| ▸ | CTSB | P07858 | 10/20 | 0.55 |
| ▸ | CTSD | P07339 | 5/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP4 | P49662 | 1/20 | 0.45 |
| ▸ | CASP5 | P51878 | 1/20 | 0.45 |
| ▸ | CASP9 | P55211 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908030 | 0.90 | CTSB (0.52) | CTSKCTSBCTSDREN | |
| SCHEMBL10431432 | 0.90 | CTSB (0.52) | CTSKCTSBRENCASP1CASP3 | |
| SCHEMBL11010919 | 0.83 | CTSB (0.44) | CTSKCTSBRENCASP1CASP3 | |
| SCHEMBL10431287 | 0.81 | CTSB (0.51) | CTSKCTSBRENCASP3 | |
| SCHEMBL10907851 | 0.76 | CTSK (0.57) | CTSKCTSBCTSDREN | |
| SCHEMBL8972993 | 0.75 | CTSK (0.70) | CTSKCTSB | |
| SCHEMBL8972996 | 0.75 | CTSK (0.70) | CTSKCTSB | |
| SCHEMBL10908074 | 0.75 | CTSK (0.56) | CTSKCTSBCTSDREN | |
| SCHEMBL10908721 | 0.74 | CTSK (0.57) | CTSKCTSBCTSDRENCASP3 | |
| SCHEMBL10908555 | 0.74 | CTSK (0.59) | CTSKCTSBCTSDREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613676-A | PEPTIDES | CIBA-GEIGY CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |