Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.59 |
| ▸ | CTSB | P07858 | 8/20 | 0.59 |
| ▸ | REN | P00797 | 2/20 | 0.51 |
| ▸ | CTSD | P07339 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909792 | 0.89 | CTSB (0.55) | CTSKCTSBRENCTSD | |
| SCHEMBL10431103 | 0.88 | CTSL (0.61) | CTSKCTSB | |
| SCHEMBL10908721 | 0.87 | CTSK (0.57) | CTSKCTSBRENCTSD | |
| SCHEMBL10907851 | 0.82 | CTSK (0.57) | CTSKCTSBRENCTSD | |
| SCHEMBL11006634 | 0.81 | REN (0.49) | CTSKCTSBREN | |
| SCHEMBL31512923 | 0.80 | CTSK (0.69) | CTSKCTSB | |
| SCHEMBL31512934 | 0.80 | CTSK (0.69) | CTSKCTSB | |
| SCHEMBL31512942 | 0.80 | CTSK (0.69) | CTSKCTSB | |
| SCHEMBL8972996 | 0.79 | CTSK (0.70) | CTSKCTSB | |
| SCHEMBL8972993 | 0.79 | CTSK (0.70) | CTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613676-A | PEPTIDES | CIBA-GEIGY CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |