SCHEMBL10907836

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@H](C(=O)NC(=O)COc1ccc(O)c(C(N)=O)c1)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	PTPN1	P18031	1/20	0.48

▸	CTSK	P43235	7/20	0.44

▸	CTSB	P07858	6/20	0.44

▸	CAPN1	P07384	2/20	0.44

▸	REN	P00797	6/20	0.43

▸	HTRA1	Q92743	1/20	0.43

▸	CTSL	P07711	1/20	0.41

▸	CTSS	P25774	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10905545	0.89	CTSK (0.54)	PTPN1CTSKCTSBCTSLCTSS
SCHEMBL10908060	0.82	CTSK (0.51)	PTPN1CTSKCTSBCAPN1REN
SCHEMBL10909559	0.82	CTSK (0.51)	PTPN1CTSKCTSBCAPN1REN
SCHEMBL10905628	0.81	CTSK (0.47)	PTPN1CTSKCTSBCAPN1REN
SCHEMBL10905777	0.81	CTSK (0.49)	PTPN1CTSKCTSBCAPN1REN
SCHEMBL10909457	0.81	REN (0.54)	CTSKCTSBCAPN1RENHTRA1
SCHEMBL10557771	0.80	PTPN1 (0.43)	PTPN1CAPN1RENHTRA1CTSL
SCHEMBL10909548	0.79	CTSB (0.53)	CTSKCTSBREN
SCHEMBL10907948	0.79	REN (0.48)	CTSKCTSBCAPN1RENHTRA1
SCHEMBL10908231	0.79	CTSK (0.47)	CTSKCTSBCAPN1RENHTRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4613676-A	PEPTIDES	CIBA-GEIGY CORPORATION (US)	1986-09-23	—	—	US	disclosed