Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.58 |
| ▸ | CTSB | P07858 | 3/20 | 0.58 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.54 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 4/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | REN | P00797 | 5/20 | 0.51 |
| ▸ | CTSD | P07339 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908191 | 0.97 | CTSK (0.59) | CTSKCTSBCAPN1CAPN2CTSL | |
| SCHEMBL10909782 | 0.88 | REN (0.48) | CTSKCTSBCAPN1RENCTSD | |
| SCHEMBL10907948 | 0.85 | REN (0.48) | CTSKCTSBCAPN1RENCTSD | |
| SCHEMBL8653583 | 0.83 | CTSK (0.71) | CTSKCTSBCAPN1CAPN2CTSL | |
| SCHEMBL10908003 | 0.81 | REN (0.52) | RENCTSD | |
| SCHEMBL4862861 | 0.80 | CTSK (0.72) | CTSKCTSBCAPN1CTSLCTSS | |
| SCHEMBL9819550 | 0.80 | CTSK (0.63) | CTSKCTSBCAPN1CTSLCTSS | |
| SCHEMBL30480137 | 0.80 | CTSK (0.60) | CTSKCTSBCAPN1CTSLCTSS | |
| SCHEMBL10908433 | 0.80 | CTSK (0.53) | CTSKCTSBCAPN1CAPN2CTSL | |
| SCHEMBL24049786 | 0.79 | CTSK (0.71) | CTSKCTSBCTSLCTSSREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613676-A | PEPTIDES | CIBA-GEIGY CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |