Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.72 |
| ▸ | CTSL | P07711 | 6/20 | 0.66 |
| ▸ | CTSS | P25774 | 4/20 | 0.66 |
| ▸ | CTSB | P07858 | 2/20 | 0.65 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.62 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933303 | 0.94 | CAPN1 (0.65) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL30407074 | 0.92 | CTSK (0.71) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL7607055 | 0.92 | CTSK (0.69) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL16463509 | 0.92 | CTSK (0.69) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5490787 | 0.92 | CTSK (0.64) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL4576421 | 0.91 | CTSK (0.65) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL16984912 | 0.91 | CTSK (0.65) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL25977611 | 0.91 | CTSK (0.65) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL9819550 | 0.91 | CTSK (0.63) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL30480137 | 0.91 | CTSK (0.60) | CTSKCTSLCTSSCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390804-B2 | N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-06-24 | — | — | US | disclosed |
| US-7390804-B2 | N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-06-24 | — | — | US | disclosed |
| US-7390804-B2 | N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-06-24 | — | — | US | disclosed |
| US-20050164954-A1 | N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2005-07-28 | — | — | US | disclosed |
| US-6900207-B2 | N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20030153508-A1 | Nitrogen-containing 5-membered cyclic compounds and drugs containing these compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-08-14 | — | — | US | disclosed |
| EP-1254901-A1 | NITROGEN-CONTAINING 5-MEMBERED CYCLIC COMPOUNDS AND DRUGS CONTAINING THESE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050164954-A1 | N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient | ACIN1, CASP7, CASP10 | CTSK 138/4885CTSL 32/4885CTSS 4/4885 |
| US-20030153508-A1 | Nitrogen-containing 5-membered cyclic compounds and drugs containing these compounds as the active ingredient | ACIN1, CASP7, CASP10 | CTSK 396/4885CTSL 55/4885CTSS 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.