Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.60 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | CD40 | P25942 | 2/20 | 0.42 |
| ▸ | CD40LG | P29965 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11343839 | 0.92 | ENPP2 (0.60) | ENPP2CASP6CTDSP1TIMP3DEGS1 | |
| SCHEMBL10907747 | 0.89 | ENPP2 (0.51) | ENPP2TIMP3DEGS1NPC1RAB9A | |
| SCHEMBL11427784 | 0.89 | CASP6 (0.60) | ENPP2CASP6CTDSP1TIMP3NQO2 | |
| SCHEMBL10909144 | 0.86 | ENPP2 (0.56) | ENPP2CASP6CTDSP1TIMP3DEGS1 | |
| SCHEMBL10909132 | 0.85 | ENPP2 (0.50) | ENPP2CASP6CTDSP1TIMP3DEGS1 | |
| SCHEMBL11434109 | 0.84 | CD40 (0.56) | ENPP2CASP6CD40CD40LGCA1 | |
| SCHEMBL10908526 | 0.83 | ENPP2 (0.45) | ENPP2NT5ECA1CA2NPC1 | |
| SCHEMBL10908058 | 0.82 | ENPP2 (0.54) | ENPP2CASP6CTDSP1TIMP3DEGS1 | |
| SCHEMBL11342897 | 0.81 | KMT2A (0.53) | ENPP2TIMP3NPC1RAB9AMEN1 | |
| SCHEMBL11441385 | 0.81 | ENPP2 (0.51) | ENPP2CASP6CTDSP1DEGS1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |