Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907981 | 0.89 | ENPP2 (0.60) | CASP6CTDSP1ENPP2POLBMEN1 | |
| SCHEMBL11343839 | 0.89 | ENPP2 (0.60) | CASP6CTDSP1ENPP2PRMT1SNCA | |
| SCHEMBL10326996 | 0.88 | ENPP2 (0.71) | CASP6CTDSP1ENPP2POLBMEN1 | |
| SCHEMBL11441389 | 0.87 | ULK1 (0.52) | CASP6CTDSP1ENPP2MEN1KMT2A | |
| SCHEMBL11425014 | 0.85 | CASP6 (0.57) | CASP6CTDSP1ENPP2POLBMEN1 | |
| SCHEMBL11440357 | 0.85 | ENPP2 (0.51) | CASP6CTDSP1ENPP2MEN1KMT2A | |
| SCHEMBL11441385 | 0.85 | ENPP2 (0.51) | CASP6CTDSP1ENPP2MEN1KMT2A | |
| SCHEMBL14679078 | 0.84 | CASP6 (0.54) | CASP6CTDSP1ENPP2POLBMEN1 | |
| SCHEMBL11434109 | 0.83 | CD40 (0.56) | CASP6ENPP2POLBMEN1KMT2A | |
| SCHEMBL11433010 | 0.82 | CASP6 (0.67) | CASP6CTDSP1ENPP2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |