Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11349148 | 0.93 | DHODH (0.43) | DHODHTAS1R3TAS1R1TAS1R2MAPT | |
| SCHEMBL11428049 | 0.86 | MEN1 (0.41) | DHODHMAPTMEN1KMT2ARAB9A | |
| SCHEMBL10907766 | 0.85 | ALDH1A1 (0.43) | DHODHTAS1R3TAS1R1TAS1R2MAPT | |
| SCHEMBL11440740 | 0.84 | MEN1 (0.41) | MAPTMEN1KMT2ARAB9ACYP1A2 | |
| SCHEMBL10905198 | 0.84 | DHODH (0.43) | DHODHTAS1R3TAS1R1TAS1R2MAPT | |
| SCHEMBL10909707 | 0.83 | CD40 (0.45) | MAPTMEN1KMT2ATERTTOP1 | |
| SCHEMBL11442387 | 0.83 | MEN1 (0.53) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10907651 | 0.81 | NPC1 (0.45) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL11426750 | 0.81 | MEN1 (0.60) | MAPTMEN1KMT2ARAB9ACYP1A2 | |
| SCHEMBL11428577 | 0.80 | HDAC1 (0.51) | MAPTMEN1KMT2ARAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |