Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 1/20 | 0.45 |
| ▸ | CD40LG | P29965 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11344807 | 0.93 | TIMP3 (0.48) | CD40CD40LGCA2APEX1HDAC1 | |
| SCHEMBL10907651 | 0.88 | NPC1 (0.45) | APEX1MEN1KMT2ACCR8TIMP3 | |
| SCHEMBL11428577 | 0.86 | HDAC1 (0.51) | CA2APEX1HDAC1CA1MEN1 | |
| SCHEMBL10908002 | 0.83 | DHODH (0.43) | MEN1KMT2ATERTTOP1POLB | |
| SCHEMBL10907563 | 0.82 | CD40 (0.50) | CD40CD40LGCA2APEX1MEN1 | |
| SCHEMBL10907840 | 0.82 | CD40 (0.43) | CD40CD40LGCA2CA1MEN1 | |
| SCHEMBL10907614 | 0.82 | LMNA (0.41) | MEN1KMT2AHPGDPOLBMAPT | |
| SCHEMBL11423374 | 0.82 | NPC1 (0.60) | CD40CD40LGMEN1KMT2ACTDSP1 | |
| SCHEMBL11350051 | 0.81 | KMT2A (0.53) | APEX1MEN1KMT2ATIMP3POLB | |
| SCHEMBL10976824 | 0.81 | CYP2D6 (0.49) | CD40CD40LGCA2APEX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |