Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | CBX7 | O95931 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11344516 | 0.93 | TRPV1 (0.49) | ALDH1A1HPSEMAPTMEN1KMT2A | |
| SCHEMBL11426177 | 0.88 | HPSE (0.42) | ALDH1A1HPSEMAPTMEN1KMT2A | |
| SCHEMBL11440869 | 0.87 | HPSE (0.42) | ALDH1A1HPSEMAPTMEN1KMT2A | |
| SCHEMBL10908002 | 0.85 | DHODH (0.43) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL10907840 | 0.85 | CD40 (0.43) | MEN1KMT2ATIMP3RAB9ANPC1 | |
| SCHEMBL10908078 | 0.85 | HPSE (0.44) | ALDH1A1HPSEMAPTMEN1KMT2A | |
| SCHEMBL11433673 | 0.84 | HPGD (0.52) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL10909111 | 0.84 | KMT2A (0.47) | ALDH1A1HPSEMAPTMEN1KMT2A | |
| SCHEMBL11423367 | 0.83 | HPGD (0.61) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL10908628 | 0.82 | HPSE (0.47) | ALDH1A1HPSEMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |