Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 7/20 | 0.48 |
| ▸ | CD40 | P25942 | 1/20 | 0.45 |
| ▸ | CD40LG | P29965 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 2/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11339195 | 0.93 | TIMP3 (0.48) | MPLCD40CD40LGCASP6NSD2 | |
| SCHEMBL10907712 | 0.91 | MPL (0.46) | MPLCD40CD40LGCASP6ENPP2 | |
| SCHEMBL9343077 | 0.88 | MPL (0.50) | MPLCASP6NSD2MMP14CTRC | |
| SCHEMBL10908320 | 0.88 | KMT2A (0.45) | MPLNSD2KMT2AMEN1HPGD | |
| SCHEMBL10907955 | 0.86 | CD40 (0.44) | CD40CD40LGCASP6ENPP2KMT2A | |
| SCHEMBL11433587 | 0.86 | CASP6 (0.49) | MPLCASP6NSD2MMP14SNCA | |
| SCHEMBL11347286 | 0.84 | TIMP3 (0.49) | MPLCD40CD40LGCASP6KMT2A | |
| SCHEMBL10907534 | 0.82 | CD40 (0.50) | MPLCD40CD40LGENPP2KMT2A | |
| SCHEMBL10909346 | 0.82 | CD40 (0.43) | CD40CD40LGCASP6ENPP2KMT2A | |
| SCHEMBL10909512 | 0.82 | ALDH1A1 (0.40) | MPLCD40CD40LGNSD2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |