Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | RECQL | P46063 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | TIMP3 | P35625 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.43 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.43 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337777 | 0.93 | TIMP3 (0.54) | KMT2AMEN1RECQLHSD17B10TDP1 | |
| SCHEMBL10908295 | 0.89 | KMT2A (0.45) | KMT2AMEN1RECQLHSD17B10TDP1 | |
| SCHEMBL10909346 | 0.89 | CD40 (0.43) | KMT2AMEN1RECQLTIMP3TNNI3 | |
| SCHEMBL10907950 | 0.86 | MEN1 (0.47) | KMT2AMEN1RECQLHSD17B10TDP1 | |
| SCHEMBL10907462 | 0.86 | TNNI3 (0.53) | KMT2AMEN1RECQLHSD17B10TDP1 | |
| SCHEMBL11440921 | 0.85 | ALDH1A1 (0.48) | KMT2AMEN1RECQLHSD17B10TDP1 | |
| SCHEMBL10908320 | 0.85 | KMT2A (0.45) | KMT2AMEN1RECQLHSD17B10TDP1 | |
| SCHEMBL10905262 | 0.83 | BRAF (0.40) | KMT2AMEN1RECQLHSD17B10TDP1 | |
| SCHEMBL10908081 | 0.83 | KMT2A (0.46) | KMT2AMEN1RECQLHSD17B10TDP1 | |
| SCHEMBL11339069 | 0.82 | KMT2A (0.53) | KMT2AMEN1RECQLHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |