Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.64 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912936 | 0.82 | CTSB (0.62) | CTSBCTSLNFKB1NFKB2RELA | |
| SCHEMBL10910910 | 0.82 | CTSB (0.43) | CTSBCTSLPDE4DNFKB1NFKB2 | |
| SCHEMBL12599530 | 0.79 | CTSB (0.58) | CTSBCTSLPDE4DNFKB1NFKB2 | |
| SCHEMBL28150498 | 0.78 | CTSB (1.00) | CTSBCTSLNFKB1NFKB2RELA | |
| SCHEMBL9752750 | 0.73 | FFAR1 (0.67) | FFAR1MEN1KMT2A | |
| SCHEMBL31544925 | 0.71 | CTSB (0.46) | CTSBCTSLPDE4DNFKB1NFKB2 | |
| SCHEMBL14249407 | 0.68 | NFKB1 (0.63) | CTSBCTSLPDE4DNFKB1NFKB2 | |
| SCHEMBL31040526 | 0.68 | FFAR1 (0.59) | FFAR1MEN1KMT2A | |
| SCHEMBL31040534 | 0.68 | FFAR1 (0.59) | FFAR1MEN1KMT2APOLB | |
| SCHEMBL31040527 | 0.68 | FFAR1 (0.59) | FFAR1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069536-B1 | PHLOROPHENONE DERIVATIVES, PROCESSES FOR PREPARING SUCH COMPOUNDS, USES AND PHARMACEUTICAL COMPOSITIONS OF PHLOROPHENONE COMPOUNDS | NORISTAN LIMITED (ZA) | 1986-12-17 | — | — | EP | disclosed |
| US-4578520-A | Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds | NORISTAN LIMITED (ZA) | 1986-03-25 | — | — | US | disclosed |
| US-4503256-A | BACTERICIDES, FUNGICIDES | NORISTAN LIMITED (ZA) | 1985-03-05 | — | — | US | disclosed |
| EP-0069536-A1 | Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds | NORISTAN LIMITED (ZA) | 1983-01-12 | — | — | EP | disclosed |