Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.62 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.56 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908576 | 0.82 | CTSB (0.64) | CTSBFFAR1CTSLMEN1KMT2A | |
| SCHEMBL10908300 | 0.82 | PLA2G2A (0.53) | CTSBPLA2G2APLA2G5FFAR1CTSL | |
| Didodecanoylphloroglucinol SCHEMBL9188500 | 0.73 | PLA2G2A (1.00) | PLA2G2APLA2G5FFAR1ELANEMEN1 | |
| SCHEMBL14924223 | 0.73 | PLA2G2A (1.00) | PLA2G2APLA2G5FFAR1ELANEMEN1 | |
| SCHEMBL9752712 | 0.73 | PLA2G2A (1.00) | PLA2G2APLA2G5FFAR1ELANEMEN1 | |
| SCHEMBL9752843 | 0.73 | PLA2G2A (1.00) | PLA2G2APLA2G5FFAR1ELANEMEN1 | |
| SCHEMBL9752583 | 0.72 | PLA2G2A (0.96) | PLA2G2APLA2G5FFAR1ELANEMEN1 | |
| SCHEMBL10910390 | 0.72 | CTSB (0.46) | CTSBPLA2G2APLA2G5FFAR1CTSL | |
| SCHEMBL18270705 | 0.71 | CTSB (0.46) | CTSBALDH1A1 | |
| SCHEMBL10911004 | 0.69 | CTSB (0.45) | CTSBPLA2G2APLA2G5FFAR1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069536-B1 | PHLOROPHENONE DERIVATIVES, PROCESSES FOR PREPARING SUCH COMPOUNDS, USES AND PHARMACEUTICAL COMPOSITIONS OF PHLOROPHENONE COMPOUNDS | NORISTAN LIMITED (ZA) | 1986-12-17 | — | — | EP | disclosed |
| US-4578520-A | Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds | NORISTAN LIMITED (ZA) | 1986-03-25 | — | — | US | disclosed |
| US-4503256-A | BACTERICIDES, FUNGICIDES | NORISTAN LIMITED (ZA) | 1985-03-05 | — | — | US | disclosed |
| EP-0069536-A1 | Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds | NORISTAN LIMITED (ZA) | 1983-01-12 | — | — | EP | disclosed |