SCHEMBL1759366

SCHEMBL1759366

C[Si](C)(C)OC(=O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.58
LMNA P02545 2/20 0.56
F2 P00734 1/20 0.56
TP53 P04637 1/20 0.52
ALDH1A1 P00352 5/20 0.48
TDP1 Q9NUW8 4/20 0.48
HSD17B10 Q99714 1/20 0.48
KMT2A Q03164 4/20 0.45
MAPT P10636 3/20 0.45
SLC6A3 Q01959 2/20 0.45
MAPK1 P28482 1/20 0.45
HIF1A Q16665 1/20 0.45
POLB P06746 1/20 0.45
SLC6A2 P23975 1/20 0.45
CES2 O00748 2/20 0.44
CES1 P23141 2/20 0.44
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203317 0.91 TSHR (0.58) TSHRLMNAF2TP53ALDH1A1
SCHEMBL8460883 0.88 CA1 (0.44) TSHRLMNAF2TP53ALDH1A1
SCHEMBL7070049 0.86 TSHR (0.58) TSHRLMNAF2TP53ALDH1A1
SCHEMBL11091233 0.84 LOXL2 (0.42) TSHRLMNAF2TP53ALDH1A1
SCHEMBL10917868 0.84 HPGD (0.54) TSHRTP53ALDH1A1KMT2AMAPT
SCHEMBL28346238 0.83 TSHR (0.54) TSHRLMNAF2TP53ALDH1A1
SCHEMBL10922759 0.82 KDM4E (0.47) TSHRLMNAALDH1A1TDP1HSD17B10
SCHEMBL12212913 0.82 PDCD1 (0.46) LMNAALDH1A1TDP1HSD17B10KMT2A
SCHEMBL10733991 0.81 LMNA (0.61) TSHRLMNAF2TP53ALDH1A1
SCHEMBL10931509 0.80 CA12 (0.59) TSHRLMNAALDH1A1TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410357-A Multi-element external electron donor composition and application thereof 中国石油天然气股份有限公司 2023-07-11 CN claimed
CN-112684070-A Method for measuring semi-volatile organic compounds in solid waste 山东微谱检测技术有限公司 2021-04-20 CN claimed
JP-59105004-A None JP disclosed
JP-1006007-A None JP disclosed
US-12565597-B2 Electronic device DAIKIN INDUSTRIES, LTD. (JP) 2026-03-03 US disclosed
US-12434998-B2 Resin-coated ultra-thin glass TORAY INDUSTRIES, INC. (JP) 2025-10-07 US disclosed
EP-3747930-B1 FLUORO (POLY)ETHER GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2024-05-15 EP disclosed
EP-3747931-B1 ELECTRONIC DEVICE DAIKIN IND LTD (JP) 2024-03-06 EP disclosed
US-20230365458-A1 RESIN-COATED ULTRA-THIN GLASS TORAY INDUSTRIES, INC. (JP) 2023-11-16 US disclosed
CN-110573964-B Negative photosensitive resin composition and cured film 东丽株式会社 2023-11-03 CN disclosed
CN-116648353-A Resin coated ultra-thin plate glass 东丽株式会社 2023-08-25 CN disclosed
EP-0404519-A2 A process for producing a high-stiffness polypropylene CHISSO CORPORATION (JP) 1990-12-27 EP disclosed
JP-S646007-A PRODUCTION OF ALPHA-OLEFIN POLYMER CHISSO CORP 1989-01-10 JP disclosed
EP-0043630-B1 IMPROVED PROCESS FOR THE SILYLATION OF ORGANIC COMPOUNDS WITH 1,1,1-TRIMETHYL-N-(TRIMETHYLSILYL)SILANAMINE BY MEANS OF CATALYSIS WITH CERTAIN NITROGEN CONTAINING COMPOUNDS GIST-BROCADES N.V. (NL) 1986-01-08 EP disclosed
US-4470932-A TRIMETHYL SILYL CARBOXYLATE AND CARBOXYLIC ACID CHLORIDE BAYER AKTIENGESELLSCHAFT (DE) 1984-09-11 US disclosed
JP-S59105004-A POLYMERIZATION OF ETHYLENE UBE IND LTD 1984-06-18 JP disclosed
US-4400509-A WITH HEXAMETHYLDISILANE WITH AN ORGANONITROGEN CATALYST GIST-BROCADES N.V. (NL) 1983-08-23 US disclosed
EP-0043630-A2 Improved process for the silylation of organic compounds with 1,1,1-trimethyl-N-(trimethylsilyl)silanamine by means of catalysis with certain nitrogen containing compounds GIST-BROCADES N.V. (NL) 1982-01-13 EP disclosed
US-4135045-A PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1979-01-16 US disclosed
US-4048415-A TITANIUM-ALUMINUM COORDINATION CATALYSTS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1977-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565597-B2 Electronic device SELE, CX3CR1, ESR1 TSHR 477/4885LMNA 2245/4885F2 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.