SCHEMBL7070049

SCHEMBL7070049

C[Si](OC(=O)c1ccccc1)(OC(=O)c1ccccc1)OC(=O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.58
LMNA P02545 2/20 0.56
F2 P00734 1/20 0.56
ALDH1A1 P00352 5/20 0.48
TDP1 Q9NUW8 4/20 0.48
HSD17B10 Q99714 1/20 0.48
TP53 P04637 1/20 0.47
KMT2A Q03164 4/20 0.45
MAPT P10636 3/20 0.45
SLC6A3 Q01959 2/20 0.45
MAPK1 P28482 1/20 0.45
HIF1A Q16665 1/20 0.45
POLB P06746 1/20 0.45
SLC6A2 P23975 1/20 0.45
CES2 O00748 2/20 0.44
CES1 P23141 2/20 0.44
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1759366 0.86 TSHR (0.58) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL203317 0.86 TSHR (0.58) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL28346238 0.83 TSHR (0.54) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL10733991 0.81 LMNA (0.61) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL7557304 0.79 TDP1 (0.52) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL202539 0.79 LMNA (0.52) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL11729732 0.79 LMNA (0.58) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL863320 0.78 TSHR (0.59) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL10908802 0.78 TSHR (0.48) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL10912113 0.78 TSHR (0.48) TSHRLMNAF2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119875573-A Transparent deacidification type long-acting mildew-proof silicone sealant 合盛硅业(嘉兴)有限公司 2025-04-25 CN claimed
CN-119875573-A Transparent deacidification type long-acting mildew-proof silicone sealant 合盛硅业(嘉兴)有限公司 2025-04-25 CN disclosed
CN-119875573-A Transparent deacidification type long-acting mildew-proof silicone sealant 合盛硅业(嘉兴)有限公司 2025-04-25 CN disclosed
EP-0771855-B1 Crosslinked emulsions of pre-formed silicon-modified organic polymers DOW CORNING (US) 2003-06-18 EP disclosed
US-5895794-A Shelf stable cross-linked emulsions with optimum consistency and handling without the use of thickeners DOW CORNING CORPORATION (US) 1999-04-20 US disclosed
US-5840800-A Crosslinked emulsions of pre-formed silicon modified organic polymers DOW CORNING CORPORATION (US) 1998-11-24 US disclosed
EP-0771855-A2 Crosslinked emulsions of pre-formed silicon-modified organic polymers DOW CORNING CORPORATION (US) 1997-05-07 EP disclosed
EP-0739928-A2 Crosslinked emulsions with optimum consistency and handling without thickeners DOW CORNING CORPORATION (US) 1996-10-30 EP disclosed
US-5321075-A Gives a silicone elastomer upon removal of water DOW CORNING CORPORATION (US) 1994-06-14 US disclosed