Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908934 | 0.96 | TDP1 (0.61) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11623713 | 0.89 | TDP1 (0.64) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL5426518 | 0.84 | TDP1 (0.58) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL9510812 | 0.84 | TDP1 (0.58) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL5397492 | 0.84 | TDP1 (0.58) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL24089572 | 0.78 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL26543 | 0.78 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL9754130 | 0.78 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL9665188 | 0.78 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL121233 | 0.78 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613617-A | Synergistic insecticidal compositions containing dione esters | UNION CARBIDE CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |