Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Permethrin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 1/20 | 1.00 |
| ▸ | CNR1 | P21554 | 1/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Permethrin SCHEMBL29397229 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL29442911 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL9665188 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL9669087 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL117908 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL910678 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL24089572 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL9754130 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL26543 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL584812 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4595 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260137082-A1 | FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL | SYNGENTA CROP PROTECTION AG (CH) | 2026-05-21 | — | — | US | claimed |
| EP-4720012-A1 | HYDRAULIC BINDER COMPOSITIONS FOR FLOORING APPLICATIONS | Ecocem Materials Limited (IE) | 2026-04-08 | — | — | EP | claimed |
| US-12583792-B2 | Cement additives for rapid strength development | CEMVISION AB (SE) | 2026-03-24 | — | — | US | claimed |
| EP-4692018-A1 | METHOD FOR MANUFACTURING CSA-TYPE CEMENT | Heidelberg Materials AG (DE) | 2026-02-11 | — | — | EP | claimed |
| WO-2025262358-A1 | BELITE CEMENT | UPM-KYMMENE CORPORATION (FI) | 2025-12-26 | — | — | WO | claimed |
| WO-2025244856-A1 | METHODS AND COMPOSITIONS RELATING TO ELQ COMPOUNDS | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2025-11-27 | — | — | WO | claimed |
| EP-3060043-B1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | CORTEVA AGRISCIENCE LLC (US) | 2025-11-26 | — | — | EP | claimed |
| EP-3578542-B1 | COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2025-11-12 | — | — | EP | claimed |
| US-20250324983-A1 | METHOD AND APPARATUS FOR CONTROLLING ARTHROPODS USING MASSOIA ESSENTIAL OIL AND RELATED PYRONES | US AGRICULTURE (US) | 2025-10-23 | — | — | US | claimed |
| US-20250320160-A1 | A TERNARY HYDRAULIC BINDER COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2025-10-16 | — | — | US | claimed |
| EP-1703792-A1 | PESTICIDALLY ACTIVE COMBINATIONS | Syngenta Participations AG (CH) | 2006-09-27 | — | — | EP | claimed |
| WO-2006037632-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2006-04-13 | — | — | WO | claimed |
| WO-2006037633-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2006-04-13 | — | — | WO | claimed |
| WO-2006037634-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2006-04-13 | — | — | WO | claimed |
| WO-2006015865-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2006-02-16 | — | — | WO | claimed |
| WO-2005053407-A1 | PESTICIDALLY ACTIVE COMBINATIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2005-06-16 | — | — | WO | claimed |
| WO-2004082382-A1 | SYNERGISTIC HERBICIDAL COMPOSITION COMPRISING A HERBICIDALLY ACTIVE COMPOUND IN COMBINATION WITH AN INSECTICIDE | SYNGENTA PARTICIPATIONS AG (CH) | 2004-09-30 | — | — | WO | claimed |
| US-20030198659-A1 | Fibrous pest control | CORNELL RESEARCH FOUNDATION, INC. | 2003-10-23 | — | — | US | claimed |
| US-20020042394-A1 | Cobalamin compounds useful as antibiotic agents and as imaging agents | HOGENKAMP HENRICUS P C (US) | 2002-04-11 | — | — | US | claimed |
| WO-2001092288-A2 | COBALAMIN COMPOUNDS USEFUL AS ANTIBIOTIC AGENTS AND AS IMAGING AGENTS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2001-12-06 | — | — | WO | claimed |