Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.67 |
| ▸ | MAOB | P27338 | 10/20 | 0.67 |
| ▸ | TLR4 | O00206 | 6/20 | 0.67 |
| ▸ | TLR2 | O60603 | 6/20 | 0.67 |
| ▸ | BACE1 | P56817 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909084 | 1.00 | MAOA (0.67) | MAOAMAOBTLR4TLR2BACE1 | |
| SCHEMBL1646385 | 0.85 | BACE1 (0.61) | MAOAMAOBTLR4TLR2BACE1 | |
| SCHEMBL31053128 | 0.85 | BACE1 (0.61) | MAOAMAOBTLR4TLR2BACE1 | |
| SCHEMBL4888283 | 0.85 | MAOA (0.63) | MAOAMAOBTLR4TLR2BACE1 | |
| SCHEMBL4888277 | 0.85 | MAOA (0.63) | MAOAMAOBTLR4TLR2BACE1 | |
| SCHEMBL6372335 | 0.84 | BACE1 (0.60) | MAOAMAOBTLR4TLR2BACE1 | |
| SCHEMBL11839066 | 0.84 | BACE1 (0.61) | MAOAMAOBTLR4TLR2BACE1 | |
| SCHEMBL11839076 | 0.84 | BACE1 (0.61) | MAOAMAOBTLR4TLR2BACE1 | |
| SCHEMBL8010330 | 0.83 | TLR4 (0.54) | MAOAMAOBTLR4TLR2BACE1 | |
| SCHEMBL8010335 | 0.83 | TLR4 (0.54) | MAOAMAOBTLR4TLR2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4595765-A | Process for preparing 5,6-dihydroxyindole | CLAIROL INCORPORATED (US) | 1986-06-17 | — | — | US | disclosed |