SCHEMBL10909142

SCHEMBL10909142

ClCCCc1nc(Cl)nc(Cl)n1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
TSHR P16473 2/20 0.42
ALOX15 P16050 1/20 0.42
CASP1 P29466 1/20 0.35
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10911172 0.92 ALDH1A1 (0.40) ALDH1A1TSHRALOX15CASP1
SCHEMBL10039907 0.86 ALDH1A1 (0.50) ALDH1A1TSHRALOX15CASP1
SCHEMBL4200438 0.77 ALDH1A1 (0.40) ALDH1A1TSHRALOX15CASP1
SCHEMBL1318651 0.77 ALDH1A1 (0.40) ALDH1A1TSHRALOX15CASP1TDP1
SCHEMBL447214 0.75 KMT2A (0.42) ALDH1A1TSHRALOX15CASP1
SCHEMBL11417577 0.73 KMT2A (0.44) ALDH1A1TSHRALOX15
SCHEMBL10992770 0.73 KMT2A (0.44) ALDH1A1TSHRALOX15
SCHEMBL4405124 0.73 KMT2A (0.44) ALDH1A1TSHRALOX15
SCHEMBL2328271 0.73 HRH1 (0.38) ALDH1A1TSHRALOX15CASP1
SCHEMBL11413687 0.73 KMT2A (0.44) ALDH1A1TSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4607063-A FLAME RESISTANCE THE DOW CHEMICAL COMPANY (US) 1986-08-19 US disclosed
US-4556710-A FIREPROOFING FOR POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1985-12-03 US disclosed