Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992770 | 0.98 | KMT2A (0.44) | KMT2AKCNH2ALDH1A1ALOX15TSHR | |
| SCHEMBL11417577 | 0.98 | KMT2A (0.44) | KMT2AKCNH2ALDH1A1ALOX15TSHR | |
| SCHEMBL11413687 | 0.98 | KMT2A (0.44) | KMT2AKCNH2ALDH1A1ALOX15TSHR | |
| SCHEMBL4405124 | 0.98 | KMT2A (0.44) | KMT2AKCNH2ALDH1A1ALOX15TSHR | |
| SCHEMBL1543072 | 0.95 | KMT2A (0.42) | KMT2AKCNH2ALDH1A1LMNAGPR84 | |
| SCHEMBL28637072 | 0.93 | KMT2A (0.44) | KMT2AKCNH2ALDH1A1TSHRLMNA | |
| SCHEMBL1318651 | 0.93 | ALDH1A1 (0.40) | KMT2AKCNH2ALDH1A1ALOX15TSHR | |
| SCHEMBL10911101 | 0.88 | CETP (0.36) | KMT2AKCNH2ALDH1A1ALOX15TSHR | |
| SCHEMBL8647469 | 0.86 | CASP1 (0.50) | KMT2AKCNH2ALDH1A1LMNAGPR84 | |
| Hexane SCHEMBL28831334 | 0.84 | TSHR (0.53) | KMT2AKCNH2ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | disclosed |
| US-9321735-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2016-04-26 | — | — | US | disclosed |
| US-8785630-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2014-07-22 | — | — | US | disclosed |
| US-20130267705-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2013-10-10 | — | — | US | disclosed |
| US-20130150365-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2013-06-13 | — | — | US | disclosed |
| EP-2595965-A1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | Vestaron Corporation (US) | 2013-05-29 | — | — | EP | disclosed |
| US-8389718-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2013-03-05 | — | — | US | disclosed |
| US-20120022066-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2012012528-A1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | Vestaron Corporation (US) | 2012-01-26 | — | — | WO | disclosed |
| EP-0941989-B1 | Process for the preparation of 2,4-diaryl-6-o-hydroxyphenyl-1,3,5-triazine derivatives in the presence of a protic acid catalyst | CIBA HOLDING INC (CH) | 2009-07-08 | — | — | EP | disclosed |
| EP-0937716-A2 | Process for the preparation of phenyldichloro-1,3,5-triazines | Ciba SC Holding AG (CH) | 1999-08-25 | — | — | EP | disclosed |
| US-5795905-A | 3-AMINO-5-PHENYL-1,2,4-TRIAZOLES | NEUROCRINE BIOSCIENCES, INC. (US) | 1998-08-18 | — | — | US | disclosed |
| EP-0846108-A1 | AMINO-SUBSTITUTED THIADIAZOLES, PYRIMIDINES, TRIAZINES OR TRIAZOLES USEFUL AS CTF RECEPTOR ANTAGONISTS | NEUROCRINE BIOSCIENCES, INC. (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1996039400-A1 | AMINO-SUBSTITUTED THIADIAZOLES, PYRIMIDINES, TRIAZINES OR TRIAZOLES USEFUL AS CTF RECEPTOR ANTAGONISTS | NEUROCRINE BIOSCIENCES, INC. (US) | 1996-12-12 | — | — | WO | disclosed |
| US-5438138-A | Process for the preparation of mono- and diaryltriazines | CIBA-GEIGY CORPORATION (US) | 1995-08-01 | — | — | US | disclosed |
| EP-0577559-A2 | Process for the preparation of mono- and diaryltriazines | CIBA-GEIGY AG (CH) | 1994-01-05 | — | — | EP | disclosed |
| EP-0577559-A2 | Process for the preparation of mono- and diaryltriazines | CIBA-GEIGY AG (CH) | 1994-01-05 | — | — | EP | disclosed |
| US-5106972-A | 2-METHYL-THIO-4,6-DIARYL-TRIAZINES | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| US-5084570-A | PROCESS FOR THE PREPARATION OF 2-(2',4'-DIHYDROXYPHENYL)-4,6-DIARYL-S-TRIAZINES | CIBA-GEIGY CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |
| US-4211688-A | Process for dyeing high-molecular organic material in the melt | CIBA-GEIGY CORPORATION (US) | 1980-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150365-A1 | Insecticidal Triazines and Pyrimidines | TYMS, TYMP, DHX15 | KMT2A 1053/4885KCNH2 881/4885ALDH1A1 3089/4885 |
| US-20120022066-A1 | Insecticidal Triazines and Pyrimidines | TYMS, TYMP, DHX15 | KMT2A 1053/4885KCNH2 881/4885ALDH1A1 3089/4885 |
| US-20130267705-A1 | Insecticidal Triazines and Pyrimidines | TYMS, TYMP, DHX15 | KMT2A 1053/4885KCNH2 881/4885ALDH1A1 3089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.