Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 8/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1562318 | 1.00 | HRH1 (0.38) | HRH1CA12CA1CA2CA3 | |
| SCHEMBL31162283 | 0.83 | CA12 (0.47) | HRH1CA12CA1CA2CA3 | |
| SCHEMBL19125179 | 0.80 | ALDH1A1 (0.44) | TSHRALDH1A1ALOX15CASP1 | |
| SCHEMBL10039907 | 0.80 | ALDH1A1 (0.50) | TSHRALDH1A1ALOX15LMNACASP1 | |
| SCHEMBL11413687 | 0.77 | KMT2A (0.44) | TSHRALDH1A1ALOX15LMNA | |
| SCHEMBL10992770 | 0.77 | KMT2A (0.44) | TSHRALDH1A1ALOX15LMNA | |
| SCHEMBL4405124 | 0.77 | KMT2A (0.44) | TSHRALDH1A1ALOX15LMNA | |
| SCHEMBL11417577 | 0.77 | KMT2A (0.44) | TSHRALDH1A1ALOX15LMNA | |
| SCHEMBL10673060 | 0.74 | CASP1 (0.68) | HRH1CA12CA1CA2CA3 | |
| SCHEMBL10909142 | 0.73 | ALDH1A1 (0.42) | TSHRALDH1A1ALOX15CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7999101-B2 | Genetic material complexing and internalizing capacity; low cytotoxicity; such as 2-[4-(3-amino-propylamino)-6-tetradecylamino-[1,3,5]triazin-2-ylamino]-ethanethiol or its disulphide dimer | POLITECNICO DI MILANO (IT) | 2011-08-16 | — | — | US | disclosed |
| US-20080146518-A1 | Cationic Lipids for the Transfection of Nucleic Acids | POLITECNICO DI MILANO (IL) | 2008-06-19 | — | — | US | disclosed |
| EP-1846378-A2 | CATIONIC LIPIDS FOR THE TRANSFECTION OF NUCLEIC ACIDS | Politecnico Di Milano (IT) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006087752-A2 | CATIONIC LIPIDS FOR THE TRANSFECTION OF NUCLEIC ACIDS | POLITECNICO DI MILANO (IT) | 2006-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146518-A1 | Cationic Lipids for the Transfection of Nucleic Acids | AARS1, HARS1, LPAR3 | HRH1 201/4885CA12 4624/4885CA1 4400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.