SCHEMBL10909157

SCHEMBL10909157

Cc1ccc(C(O)CCc2ccc(N)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.47
CYP2A6 P11509 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
ACHE P22303 1/20 0.45
GFER P55789 1/20 0.43
ADRB2 P07550 1/20 0.42
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
MAOA P21397 2/20 0.38
MAOB P27338 2/20 0.38
TEAD4 Q15561 1/20 0.37
IDO1 P14902 1/20 0.37
DPP4 P27487 1/20 0.37
CYP19A1 P11511 1/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
HSP90AA1 P07900 1/20 0.36
MAPK1 P28482 1/20 0.36
AGTR1 P30556 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30849662 0.83 CNR2 (0.48) ADRB2PPARGPPARAALDH1A1POLB
SCHEMBL30849680 0.83 CYP19A1 (0.45) ACHEADRB2PPARGPPARACYP19A1
SCHEMBL10021106 0.82 PPARG (0.48) CYP1A2TAAR1ADRB2PPARGPPARA
SCHEMBL30849667 0.82 PPARG (0.55) TAAR1ADRB2PPARGPPARAALDH1A1
SCHEMBL30849688 0.82 PPARG (0.48) CYP1A2TAAR1ADRB2PPARGPPARA
SCHEMBL31619965 0.82 PPARG (0.55) TAAR1ADRB2PPARGPPARAALDH1A1
SCHEMBL3083688 0.82 MAOB (0.55) CYP2A6TAAR1PPARGPPARAMAOA
SCHEMBL19152522 0.80 MMP12 (0.50) PPARGPPARATDP1
SCHEMBL14839523 0.80 ADRB2 (0.51) ADRB2PPARGPPARAIDO1ALDH1A1
SCHEMBL19255610 0.77 GFER (0.74) CYP1A2CYP2A6TAAR1ACHEGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4566900-A PRE- AND POSTEMERGENCE HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1986-01-28 US disclosed
EP-0081206-A2 Aniline derivatives, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1983-06-15 EP disclosed