SCHEMBL30849688

SCHEMBL30849688

Cc1ccc([C@H](O)CCc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.48
PPARA Q07869 1/20 0.48
RIPK1 Q13546 1/20 0.46
METAP2 P50579 1/20 0.46
METAP1 P53582 1/20 0.46
ALDH1A1 P00352 1/20 0.45
SLC6A2 P23975 3/20 0.45
SLC6A3 Q01959 3/20 0.45
CYP3A4 P08684 3/20 0.45
CYP2D6 P10635 3/20 0.45
SLC6A4 P31645 2/20 0.45
KCNH2 Q12809 2/20 0.45
CNR1 P21554 1/20 0.45
CNR2 P34972 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
UTS2R Q9UKP6 1/20 0.45
LMNA P02545 2/20 0.44
ADRA1A P35348 2/20 0.44
CYP2C19 P33261 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10021106 1.00 PPARG (0.48) PPARGPPARARIPK1METAP2METAP1
SCHEMBL30849667 0.93 PPARG (0.55) PPARGPPARARIPK1METAP2METAP1
SCHEMBL31619965 0.93 PPARG (0.55) PPARGPPARARIPK1METAP2METAP1
SCHEMBL12064809 0.91 HRH1 (0.47) RIPK1METAP2METAP1ALDH1A1CYP3A4
SCHEMBL936318 0.90 PPARG (0.50) PPARGPPARARIPK1SLC6A2SLC6A3
SCHEMBL19152522 0.90 MMP12 (0.50) PPARGPPARARIPK1TDP1L3MBTL1
SCHEMBL5835025 0.86 PPARG (0.54) PPARGPPARARIPK1SLC6A2SLC6A3
SCHEMBL477470 0.86 PPARG (0.54) PPARGPPARARIPK1SLC6A2SLC6A3
SCHEMBL499868 0.86 PPARG (0.54) PPARGPPARARIPK1SLC6A2SLC6A3
SCHEMBL30849683 0.85 RAB9A (0.50) PPARGPPARARIPK1ALDH1A1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117865776-A Method for directly converting aromatic alkyne into chiral alcohol by one-pot method 三峡大学 2024-04-12 CN disclosed