Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911286 | 0.84 | SIGMAR1 (0.42) | IDO1SIGMAR1TP53CYP1A2CYP2D6 | |
| SCHEMBL6688655 | 0.82 | HRH1 (0.44) | MAOAHTR2AHRH1SLC7A5 | |
| SCHEMBL27568690 | 0.81 | IDO1 (0.43) | IDO1SIGMAR1TP53CYP1A2CYP2D6 | |
| SCHEMBL10911204 | 0.81 | KMT2A (0.54) | HTR2AHRH1SIGMAR1TP53CYP1A2 | |
| SCHEMBL10913445 | 0.81 | SIGMAR1 (0.53) | HTR2AHRH1SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL7263992 | 0.80 | CHRNB2 (0.51) | HTR2AHRH1SLC7A5 | |
| SCHEMBL10911293 | 0.80 | SIGMAR1 (0.55) | HTR2AHRH1SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL10911235 | 0.80 | SIGMAR1 (0.55) | MAOASIGMAR1MAPT | |
| SCHEMBL27948884 | 0.79 | SLC6A2 (0.44) | IDO1SIGMAR1TP53CYP1A2CYP2D6 | |
| SCHEMBL10909185 | 0.79 | SLC6A2 (0.55) | HTR2AHRH1SIGMAR1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4620036-A | Diphenylalkanoether and diphenylalkanone oximeether derivatives | ONO KEIICHI (JP) | 1986-10-28 | — | — | US | disclosed |
| US-4602023-A | Diphenic acid monoamides | WARNER-LAMBERT COMPANY (US) | 1986-07-22 | — | — | US | disclosed |
| EP-0017217-B1 | DIPHENYLALKANOETHER AND DIPHENYLALKANONE OXIMEETHER DERIVATIVES, A PROCESS FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-03-13 | — | — | EP | disclosed |
| US-4482573-A | Diphenylalkanoether and diphenylalkanone oximeether derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-11-13 | — | — | US | disclosed |
| US-4459410-A | Diphenylalkanoether derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-07-10 | — | — | US | disclosed |
| US-4426394-A | Diphenylalkanoether and diphenylalkanone oximeether derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1984-01-17 | — | — | US | disclosed |
| US-4388469-A | Diphenylalkanoether and diphenylalkanone oximeether derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-06-14 | — | — | US | disclosed |
| EP-0017217-A2 | Diphenylalkanoether and diphenylalkanone oximeether derivatives, a process for their production, pharmaceutical compositions and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-10-15 | — | — | EP | disclosed |