Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MPL | P40238 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11348931 | 0.93 | HPSE (0.45) | HPSEDHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10909512 | 0.91 | ALDH1A1 (0.40) | HPSEDHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10908078 | 0.89 | HPSE (0.44) | HPSEDHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10905526 | 0.86 | DHODH (0.44) | HPSEDHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL11438820 | 0.85 | CASP6 (0.40) | MEN1KMT2AMAPTMPLCYP2C19 | |
| SCHEMBL10907596 | 0.85 | HPSE (0.42) | HPSEDHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL11345247 | 0.84 | HPSE (0.43) | HPSEDHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10907712 | 0.83 | MPL (0.46) | MEN1KMT2AMAPTRAB9ALMNA | |
| SCHEMBL10907848 | 0.83 | DHODH (0.44) | HPSEDHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL11433569 | 0.83 | MAPT (0.40) | KMT2AMAPTTDP1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |