Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CD40 | P25942 | 1/20 | 0.43 |
| ▸ | CD40LG | P29965 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347286 | 0.92 | TIMP3 (0.49) | MPLCTDSP1CASP6CD40CD40LG | |
| SCHEMBL10907905 | 0.91 | MPL (0.48) | MPLCTDSP1CASP6CD40CD40LG | |
| SCHEMBL10908295 | 0.89 | KMT2A (0.45) | MPLKMT2AMEN1HPGDTIMP3 | |
| SCHEMBL11435352 | 0.87 | CASP6 (0.55) | MPLCTDSP1CASP6KMT2AMEN1 | |
| SCHEMBL10909346 | 0.86 | CD40 (0.43) | CTDSP1CASP6CD40CD40LGKMT2A | |
| SCHEMBL10907652 | 0.85 | PRMT1 (0.42) | CTDSP1CASP6CD40CD40LGKMT2A | |
| SCHEMBL11339195 | 0.84 | TIMP3 (0.48) | MPLCTDSP1CASP6CD40CD40LG | |
| SCHEMBL10909175 | 0.83 | HPSE (0.41) | MPLCD40CD40LGKMT2AMEN1 | |
| SCHEMBL11422974 | 0.83 | CD40 (0.58) | CD40CD40LGKMT2AMEN1MAPT | |
| SCHEMBL10908400 | 0.82 | DEGS1 (0.42) | CTDSP1CASP6CD40CD40LGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |