Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.36 |
| ▸ | RAB9A | P51151 | 9/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | ALPI | P09923 | 2/20 | 0.36 |
| ▸ | ALPG | P10696 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718484 | 0.81 | NPC1 (0.43) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL9718487 | 0.81 | NPC1 (0.43) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL5496325 | 0.79 | ALDH1A1 (0.44) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL8858287 | 0.79 | ALDH1A1 (0.44) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL17506172 | 0.74 | NPC1 (0.46) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL27426809 | 0.72 | TRPA1 (0.56) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL4300630 | 0.71 | TRPA1 (0.39) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9718494 | 0.71 | TDP1 (0.49) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL16566766 | 0.71 | POLB (0.55) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL8763712 | 0.71 | MAPT (0.48) | NPC1RAB9AKMT2AMEN1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4624532-A | IMPROVED COLOR FOR ELECTRO-OPTICAL DISPLAYS | GENERAL ELECTRIC COMPANY (US) | 1986-11-25 | — | — | US | disclosed |
| US-4356102-A | Dichroic liquid crystal compositions containing anthraquinone-based dyes | GENERAL ELECTRIC COMPANY (US) | 1982-10-26 | — | — | US | disclosed |
| US-4308163-A | IMPROVING BLACK COLOR OF DICHROIC DYES | GENERAL ELECTRIC COMPANY (US) | 1981-12-29 | — | — | US | disclosed |