Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15571714 | 0.89 | HPGD (0.72) | TACR1LMNAALDH1A1HTTHPGD | |
| SCHEMBL9392719 | 0.81 | PLA2G1B (0.76) | TACR1LMNAALDH1A1HTTHPGD | |
| SCHEMBL7812090 | 0.80 | LMNA (0.60) | TACR1LMNAALDH1A1HTTMAPT | |
| SCHEMBL5860896 | 0.79 | ALDH1A1 (0.73) | LMNAALDH1A1HPGDMAPTCNR2 | |
| SCHEMBL7285179 | 0.79 | ALDH1A1 (0.73) | LMNAALDH1A1HPGDMAPTCNR2 | |
| SCHEMBL10766345 | 0.78 | UTS2R (0.54) | LMNAALDH1A1SMN1; SMN2CNR2CYP2D6 | |
| SCHEMBL10952833 | 0.78 | HTT (0.58) | TACR1LMNAALDH1A1HTTHPGD | |
| Fumaric Acid SCHEMBL4372762 | 0.76 | ALDH1A1 (0.53) | TACR1LMNAALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL17229250 | 0.76 | PLAAT3 (0.73) | LMNAALDH1A1HPGDL3MBTL1CYP1A2 | |
| SCHEMBL13965859 | 0.76 | HPGD (0.71) | LMNAALDH1A1HPGDSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4603145-A | Antiatherosclerotic diphenyl alkanamides | AMERICAN CYANAMID COMPANY (US) | 1986-07-29 | — | — | US | disclosed |