Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4B | O94953 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748981 | 0.88 | PTGS2 (0.50) | CYP19A1APPPTGS2PTGS1MEN1 | |
| SCHEMBL11451774 | 0.86 | CYP19A1 (0.44) | CYP19A1TDP1MEN1KMT2AMAPK1 | |
| SCHEMBL6247385 | 0.80 | CYP19A1 (0.43) | ALDH1A1TSHRNT5ECYP19A1TDP1 | |
| SCHEMBL7743184 | 0.80 | PTGS2 (0.50) | CYP19A1APPPTGS2PTGS1MEN1 | |
| SCHEMBL10717629 | 0.79 | CYP19A1 (0.42) | ALDH1A1TSHRNT5ECYP19A1TDP1 | |
| SCHEMBL6383875 | 0.78 | TDP1 (0.38) | ALDH1A1CYP19A1TDP1PTGS2PTGS1 | |
| SCHEMBL28213761 | 0.77 | TDP1 (0.37) | ALDH1A1CYP19A1TDP1PTGS2PTGS1 | |
| SCHEMBL8650958 | 0.76 | CYP19A1 (0.42) | CYP19A1TDP1MEN1KMT2AMAPK1 | |
| SCHEMBL9398232 | 0.75 | ALDH1A1 (0.53) | ALDH1A1TSHRCYP19A1TDP1APP | |
| SCHEMBL9398237 | 0.75 | ALDH1A1 (0.53) | ALDH1A1TSHRCYP19A1TDP1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4568350-A | Cold pad-batch process for dyeing silk or silk-containing fiber blends with reactive dyes | CIBA-GEIGY CORPORATION (US) | 1986-02-04 | — | — | US | disclosed |
| US-4560388-A | WITH SULFO GROUP CONTAINING FIBER REACTIVE DYE | CIBA-GEIGY CORPORATION (US) | 1985-12-24 | — | — | US | disclosed |
| US-4330469-A | Reactive dyes, processes for their manufacture and their use | CIBA-GEIGY CORPORATION (US) | 1982-05-18 | — | — | US | disclosed |
| US-4283331-A | FIBER-REACTIVE DYES | CIBA-GEIGY CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4141890-A | FIBER-REACTIVE | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |
| US-4082739-A | FIBRE-REACTIVE DYESTUFF CONTAINING A BIS-TRIAZINYLAMINO | CIBA-GEIGY AG (CH) | 1978-04-04 | — | — | US | disclosed |
| US-RE29585-E | DYEING WOOL | CIBA-GEIGY CORPORATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-4067864-A | FOR CELLULOSE OR POLYAMIDES | CIBA-GEIGY AG (CH) | 1978-01-10 | — | — | US | disclosed |
| US-4039523-A | YELLOW | CIBA-GEIGY AG (CH) | 1977-08-02 | — | — | US | disclosed |
| US-4017477-A | 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs | CIBA-GEIGY AG (CH) | 1977-04-12 | — | — | US | disclosed |
| US-4001205-A | WATER-SOLUBLE, FIBER-REACTIVE PHENYLAZODIHYDROXY, METHYL, CYANOPYRIDINE DYESTUFFS | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |
| US-4001203-A | Heavy metal complexes of azo dyestuffs containing a heterocyclic diazo component and the residue of 5-halogeno-2,3-dihydrozypyridine as coupling component | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |
| US-3971738-A | Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
| US-3956263-A | 4-Methyl-2,6-dihydroxy-3-cyanopyridine containing dyestuffs | CIBA-GEIGY AG (CH) | 1976-05-11 | — | — | US | disclosed |