Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.36 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.36 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.36 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909592 | 0.97 | LMNA (0.47) | LMNAFABP3FABP4FABP5PTGS1 | |
| SCHEMBL10805823 | 0.83 | LMNA (0.43) | LMNAFABP3FABP4FABP5PTGS1 | |
| SCHEMBL7788558 | 0.81 | LMNA (0.44) | LMNAFABP3FABP4FABP5PTGS1 | |
| SCHEMBL9567801 | 0.81 | FABP3 (0.41) | FABP3FABP4FABP5BCL2MCL1 | |
| Guaiazulene Sulfonic Acid SCHEMBL9065336 | 0.81 | LMNA (0.44) | LMNAFABP3FABP4FABP5PTGS1 | |
| SCHEMBL10909584 | 0.80 | LMNA (0.47) | LMNAPTGS1PTGS2BCL2MCL1 | |
| SCHEMBL12646158 | 0.80 | LMNA (0.43) | LMNAFABP3FABP4FABP5PTGS1 | |
| SCHEMBL10804720 | 0.80 | LMNA (0.43) | LMNAFABP3FABP4FABP5PTGS1 | |
| SCHEMBL10802071 | 0.79 | SENP2 (0.43) | LMNASENP2SENP1SUMO2SUMO1 | |
| Guaiazulene Sulfonic Acid SCHEMBL2734180 | 0.79 | LMNA (0.46) | LMNAFABP3FABP4FABP5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61180761-A | — | — | None | — | — | JP | disclosed |
| JP-S61180761-A | 6-SUBSTITUTED AZULENE DERIVATIVE SULFONIC ACID SALT, ANTIULCER AGENT, AND PREPARATION THEREOF | KOTOBUKI SEIYAKU KK | 1986-08-13 | — | — | JP | disclosed |