SCHEMBL7788558

SCHEMBL7788558

Cc1cc(S(=O)(=O)O)c2cc(C(C)C)cccc1-2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
CA2 P00918 2/20 0.40
HDAC4 P56524 2/20 0.40
HDAC8 Q9BY41 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HTT P42858 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MDM4 O15151 1/20 0.40
CA1 P00915 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
TYR P14679 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
ALOX12 P18054 1/20 0.40
CA5A P35218 1/20 0.40
MDM2 Q00987 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10804720 0.98 LMNA (0.43) LMNACA2HDAC4HDAC8ALDH1A1
SCHEMBL10805823 0.98 LMNA (0.43) LMNACA2HDAC4HDAC8ALDH1A1
SCHEMBL10804716 0.83 LMNA (0.43) LMNACA2HDAC4HDAC8ALDH1A1
SCHEMBL10803721 0.83 LMNA (0.43) LMNACA2HDAC4HDAC8ALDH1A1
Egualen SCHEMBL668397 0.82 FABP3 (0.39) LMNACA2HDAC4HDAC8ALDH1A1
SCHEMBL7791039 0.82 CA2 (0.38) LMNACA2HDAC4HDAC8ALDH1A1
SCHEMBL10909592 0.81 LMNA (0.47) LMNACA2ALDH1A1KDM4ECA1
SCHEMBL10909581 0.81 LMNA (0.47) LMNAALDH1A1SMN1; SMN2KDM4EMAPT
Egualen SCHEMBL10805301 0.81 FABP3 (0.38) LMNACA2HDAC4HDAC8ALDH1A1
Egualen SCHEMBL442214 0.81 FABP3 (0.38) LMNACA2HDAC4HDAC8ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0147915-B1 NEW AZULENE DERIVATIVES USEFUL AS ANTI-ULCERATIVE AND ANTI-FLAMMATORY AGENTS Kotobuki Seiyaku Co., Ltd. (JP) 1987-05-06 EP claimed
US-20260137609-A1 HAIR WASHING COMPOSITION KAO CORPORATION (JP) 2026-05-21 US disclosed
EP-4692288-A1 METALWORKING OIL COMPOSITION Idemitsu Kosan Co.,Ltd. (JP) 2026-02-11 EP disclosed
EP-3741352-B1 HAIR COSMETIC COMPOSITION KAO CORP (JP) 2025-08-20 EP disclosed
US-12343418-B2 Hair cosmetic KAO CORPORATION (JP) 2025-07-01 US disclosed
EP-4501413-A1 HAIR WASHING COMPOSITION Kao Corporation (JP) 2025-02-05 EP disclosed
CN-118922172-A Hair cleansing composition 花王株式会社 2024-11-08 CN disclosed
WO-2024204420-A1 METALWORKING OIL COMPOSITION 出光興産株式会社 2024-10-03 WO disclosed
US-20240225974-A9 HAIR COSMETIC KAO CORPORATION (JP) 2024-07-11 US disclosed
EP-3578162-B1 HAIR TREATMENT METHOD KAO CORP (JP) 2024-06-26 EP disclosed
US-20190038532-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2019-02-07 US disclosed
EP-3395323-A1 HAIR TREATMENT METHOD Kao Corporation (JP) 2018-10-31 EP disclosed
CN-108366943-A HAIR TREATMENT METHOD 花王株式会社 2018-08-03 CN disclosed
EP-0672405-B1 Hair treatment composition KAO CORP (JP) 2001-11-14 EP disclosed
US-6217855-B1 ELASTICITY KAO CORPORATION (JP) 2001-04-17 US disclosed
EP-0662314-B1 Method of hair treatment KAO CORP (JP) 1999-11-03 EP disclosed
EP-0529437-B1 Hair treatment composition KAO CORP (JP) 1996-07-17 EP disclosed
EP-0672405-A1 Hair treatment composition KAO CORPORATION (JP) 1995-09-20 EP disclosed
EP-0662314-A1 Method of hair treatment Kao Corporation (JP) 1995-07-12 EP disclosed
EP-0529437-A1 Hair treatment composition Kao Corporation (JP) 1993-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137609-A1 HAIR WASHING COMPOSITION TET2, PIK3C3, SMURF1 LMNA 2233/4885CA2 960/4885HDAC4 771/4885
US-12343418-B2 Hair cosmetic TYR, CUTA, MC1R LMNA 1284/4885CA2 319/4885HDAC4 65/4885
US-20190038532-A1 METHOD FOR TREATING HAIR TYR, POLR1C, CA7 LMNA 2120/4885CA2 26/4885HDAC4 1350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.