Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467542 | 0.77 | LDHA (0.40) | HMGCRCHRM1TBXA2RADRA1ALDHA | |
| SCHEMBL1947968 | 0.76 | AKR1B1 (0.41) | TSHRALDH1A1MEN1KMT2AFFAR1 | |
| Water SCHEMBL15756484 | 0.76 | — | — | |
| SCHEMBL640244 | 0.76 | — | — | |
| SCHEMBL364986 | 0.75 | LDHA (0.38) | LDHASRRFFAR3ALDH1A1HDAC3 | |
| SCHEMBL1304727 | 0.75 | LDHA (0.38) | HMGCRCHRM1TBXA2RADRA1ALDHA | |
| SCHEMBL9329052 | 0.75 | HMGCR (0.36) | HMGCRCHRM1TBXA2RADRA1ALDHA | |
| SCHEMBL994719 | 0.74 | LDHA (0.42) | HMGCRCHRM1TBXA2RADRA1ALDHA | |
| SCHEMBL28756041 | 0.73 | TSHR (0.37) | HMGCRCHRM1TBXA2RADRA1ALDHA | |
| SCHEMBL79613 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4623721-A | Synthesis of L-fructose and derivatives thereof | PURDUE RESEARCH FOUNDATION (US) | 1986-11-18 | — | — | US | disclosed |