Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL9328763 | 0.85 | SMN1; SMN2 (0.43) | GAASMN1; SMN2CYP2C19CTSSTSHR | |
| SCHEMBL2341016 | 0.83 | ALDH1A1 (0.37) | GAASMN1; SMN2MMP8ARPIK3CD | |
| SCHEMBL3248330 | 0.77 | TSHR (0.43) | HMGCRCHRM1TBXA2RADRA1AGAA | |
| SCHEMBL8495466 | 0.77 | TSHR (0.43) | HMGCRCHRM1TBXA2RADRA1AGAA | |
| SCHEMBL3565109 | 0.77 | TSHR (0.43) | HMGCRCHRM1TBXA2RADRA1AGAA | |
| SCHEMBL10909583 | 0.75 | HMGCR (0.40) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL1782336 | 0.72 | ALDH1A1 (0.38) | HMGCRCHRM1TBXA2RADRA1AGAA | |
| SCHEMBL17037419 | 0.70 | AR (0.33) | GAASMN1; SMN2MMP8ARCYP2D6 | |
| SCHEMBL8633404 | 0.70 | AR (0.33) | GAASMN1; SMN2MMP8ARCYP2D6 | |
| SCHEMBL6053893 | 0.70 | LDHA (0.38) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454728-B1 | FLUORINATED FLAVONE ACETIC ACID | UPJOHN CO (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0454728-A1 | FLUORINATED FLAVONE ACETIC ACID. | UPJOHN CO (US) | 1991-11-06 | — | — | EP | disclosed |
| WO-1990008143-A1 | FLUORINATED FLAVONE ACETIC ACID | THE UPJOHN COMPANY (US) | 1990-07-26 | — | — | WO | disclosed |