Bis(Dimethylaminethiocarbonyl)Monosulfide

Bis(Dimethylaminethiocarbonyl)Monosulfide

SCHEMBL10909720

CN(C)C(=S)SC(=S)N(C)C.[S]

nearest known ligand 0.93

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.93
MGLL Q99685 4/20 0.93
LMNA P02545 3/20 0.93
HTT P42858 3/20 0.93
TP53 P04637 3/20 0.59
HPGD P15428 3/20 0.59
ALOX15 P16050 3/20 0.59
ALOX12 P18054 3/20 0.59
HSD17B10 Q99714 3/20 0.59
MAPT P10636 3/20 0.59
KMT2A Q03164 3/20 0.59
MAPK1 P28482 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
ALDH2 P05091 2/20 0.59
HSP90AA1 P07900 2/20 0.59
CYP3A4 P08684 2/20 0.59
FBP1 P09467 2/20 0.59
PKM P14618 2/20 0.59
LOX P28300 2/20 0.59
LOXL3 P58215 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bis(Dimethylaminethiocarbonyl)Monosulfide SCHEMBL23048 0.96 ALDH1A1 (1.00) ALDH1A1MGLLLMNAHTTTP53
Bis(Dimethylaminethiocarbonyl)Monosulfide SCHEMBL28541106 0.93 ALDH1A1 (0.93) ALDH1A1MGLLLMNAHTTTP53
Thiram SCHEMBL2773357 0.79 ALDH1A1 (0.93) ALDH1A1MGLLLMNAHTTTP53
SCHEMBL7775454 0.78
SCHEMBL28497210 0.76
SCHEMBL14548414 0.76
Thiram SCHEMBL1216571 0.74 ALDH1A1 (1.00) ALDH1A1MGLLLMNAHTTTP53
Thiram SCHEMBL21144 0.74 ALDH1A1 (1.00) ALDH1A1MGLLLMNAHTTTP53
Bis(Dimethylaminethiocarbonyl)Monosulfide SCHEMBL28242206 0.74 MGLL (0.59) ALDH1A1MGLLLMNAHTTTP53
SCHEMBL10909718 0.72 MGLL (0.57) ALDH1A1MGLLLMNAHTTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4603712-A Compounded polychloroprene formulation used as an adhesive layer in the manufacture of elastomeric articles THE GATES RUBBER COMPANY (US) 1986-08-05 US disclosed