Bis(Dimethylaminethiocarbonyl)Monosulfide

Bis(Dimethylaminethiocarbonyl)Monosulfide

SCHEMBL23048

CN(C)C(=S)SC(=S)N(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 1.00
MGLL Q99685 4/20 1.00
LMNA P02545 3/20 1.00
HTT P42858 3/20 1.00
TP53 P04637 3/20 0.62
HPGD P15428 3/20 0.62
ALOX15 P16050 3/20 0.62
ALOX12 P18054 3/20 0.62
HSD17B10 Q99714 3/20 0.62
MAPT P10636 3/20 0.62
KMT2A Q03164 3/20 0.62
MAPK1 P28482 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
ALDH2 P05091 2/20 0.62
HSP90AA1 P07900 2/20 0.62
CYP3A4 P08684 2/20 0.62
FBP1 P09467 2/20 0.62
PKM P14618 2/20 0.62
LOX P28300 2/20 0.62
LOXL3 P58215 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bis(Dimethylaminethiocarbonyl)Monosulfide SCHEMBL10909720 0.96 ALDH1A1 (0.93) ALDH1A1MGLLLMNAHTTTP53
Bis(Dimethylaminethiocarbonyl)Monosulfide SCHEMBL28541106 0.96 ALDH1A1 (0.93) ALDH1A1MGLLLMNAHTTTP53
SCHEMBL7775454 0.81
SCHEMBL28497210 0.78
SCHEMBL14548414 0.78
Thiram SCHEMBL21144 0.77 ALDH1A1 (1.00) ALDH1A1MGLLLMNAHTTTP53
Thiram SCHEMBL1216571 0.77 ALDH1A1 (1.00) ALDH1A1MGLLLMNAHTTTP53
Bis(Dimethylaminethiocarbonyl)Monosulfide SCHEMBL28242206 0.77 MGLL (0.59) ALDH1A1MGLLLMNAHTTTP53
SCHEMBL10909718 0.74 MGLL (0.57) ALDH1A1MGLLLMNAHTTTP53
SCHEMBL19873388 0.74 ALDH1A1 (0.57) ALDH1A1MGLLLMNAHTTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17204 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121758838-B Rubber conveyer belt and preparation method thereof 河北黑一橡胶有限公司 2026-05-19 CN claimed
CN-122037340-A Rubber composite material with marine antifouling property and preparation method and application thereof 辽宁维航基业科技有限公司 2026-05-15 CN claimed
CN-122037149-A Aging-resistant biodegradable material and preparation method and application thereof 北京工商大学 2026-05-15 CN claimed
CN-122037329-A Double-network crosslinked carcass rubber composition of cracked carbon black-bio-based liquid rubber and preparation method thereof 中策橡胶集团股份有限公司 2026-05-15 CN claimed
CN-122037341-A High-friction anti-pollution rubber plate and preparation method thereof 衡橡科技股份有限公司 2026-05-15 CN claimed
CN-122037401-A Ethylene propylene diene monomer rubber composite material for automobile sealing strip and preparation process thereof 株洲泰信电子科技有限公司 2026-05-15 CN claimed
CN-122037406-A Halogen hydrocarbon modified elastomer and application and preparation method thereof 朝阳华兴万达轮胎有限公司 2026-05-15 CN claimed
CN-121528620-B High-strength aging-resistant overhead insulated conductor 安徽明都电力线缆有限公司 2026-05-12 CN claimed
US-12624198-B2 Rubber composition, processing method thereof, and rubber product using the same HANGZHOU XINGLU TECHNOLOGIES CO., LTD (CN) 2026-05-12 US claimed
CN-122011521-A Anti-skid wear-resistant tire fabric for forklift and preparation method thereof 江苏赛美特机械有限公司 2026-05-12 CN claimed
US-4101463-A SCRAP RUBBER, VULCANIZATION, TIRES AMERACE CORPORATION (US) 1978-07-18 US claimed
US-4098858-A DUSTLESS FREE FLOWING RUBBER ADDITIVES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-07-04 US claimed
US-4092172-A Photocurable composition comprising a copolymer of a maleic acid monoester with an α-olefine KANSAI PAINT CO., LTD. (JA) 1978-05-30 US claimed
US-4082876-A POLYVINYL CHLORIDE, SYNTHETIC RUBBER, FOAMING AGENT, VULCANIZATION ACCELERATOR LONSEAL CORPORATION (JA) 1978-04-04 US claimed
US-4062797-A DITHIOCARBAMATE AMERICAN CYANAMID COMPANY (US) 1977-12-13 US claimed
US-4043942-A Modified nickel catalyst systems and their use in reductive alkylation reactions THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-08-23 US claimed
US-4012332-A BENZOTHIAZOLE SULFENAMIDE, A THIURAM SULFIDE OR METAL DITHIOCARBAMATE, COPPER 2-MERCAPTOBENZOTHIAZOLE AMERICAN CYANAMID COMPANY (US) 1977-03-15 US claimed
US-4003843-A SILANE, THIAZOLE, GUANIDINE, THIURAM BAYER AKTIENGESELLSCHAFT (DT) 1977-01-18 US claimed
US-3994840-A DITHIOCARBAMATE SEKISUI KASEIHIN KOGYO KABUSHIKI KAISHA (JA) 1976-11-30 US claimed
US-3968062-A Use of para-tert. butyl phenol disulfide for vulcanizing chlorobutyl rubber compositions FAIRFIELD CHEMICAL SERVICES (US) 1976-07-06 US claimed