Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911891 | 0.99 | KDM4E (0.44) | KDM4EMEN1KMT2ARAB9AHTT | |
| SCHEMBL10947007 | 0.97 | KMT2A (0.44) | KDM4EMEN1KMT2ARAB9AHTT | |
| SCHEMBL10912179 | 0.97 | KMT2A (0.45) | KDM4EMEN1KMT2ARAB9AHTT | |
| SCHEMBL10912841 | 0.94 | RAB9A (0.47) | KDM4EMEN1KMT2ARAB9AHTT | |
| SCHEMBL10912510 | 0.93 | KDM4E (0.45) | KDM4EMEN1KMT2ARAB9AHTT | |
| SCHEMBL10912207 | 0.93 | RAB9A (0.46) | KDM4EMEN1KMT2ARAB9AHTT | |
| SCHEMBL10914105 | 0.91 | CYP2D6 (0.51) | KDM4EMEN1KMT2ARAB9APOLB | |
| SCHEMBL10912079 | 0.85 | RAB9A (0.45) | KDM4EMEN1KMT2ARAB9APOLB | |
| SCHEMBL10909868 | 0.82 | ALDH1A1 (0.46) | KDM4EMEN1KMT2ARAB9APOLB | |
| Dimethylamine SCHEMBL10913743 | 0.82 | RAB9A (0.41) | MEN1KMT2ARAB9AHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |