Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912841 | 0.92 | RAB9A (0.47) | RAB9ANPC1KMT2AMEN1HPGD | |
| SCHEMBL10912207 | 0.91 | RAB9A (0.46) | RAB9ANPC1KMT2AMEN1HPGD | |
| SCHEMBL10911850 | 0.88 | HRH2 (0.47) | RAB9ANPC1KMT2AMEN1HPGD | |
| SCHEMBL10912510 | 0.86 | KDM4E (0.45) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10909796 | 0.85 | KDM4E (0.44) | RAB9ANPC1KMT2AMEN1TSHR | |
| SCHEMBL10947007 | 0.84 | KMT2A (0.44) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10911891 | 0.84 | KDM4E (0.44) | RAB9ANPC1KMT2AMEN1TSHR | |
| SCHEMBL10914105 | 0.83 | CYP2D6 (0.51) | RAB9ANPC1KMT2AMEN1TSHR | |
| SCHEMBL10912179 | 0.82 | KMT2A (0.45) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10914068 | 0.82 | PABPC1 (0.45) | RAB9ANPC1KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |