SCHEMBL10909815

SCHEMBL10909815

CC1C(=O)N(SC(Cl)(Cl)Cl)C(=O)N1c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
HTT P42858 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 2/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
HIF1A Q16665 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAOA P21397 1/20 0.34
SMO Q99835 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10909817 0.76 MAOA (0.37) ALDH1A1HTTKMT2ALMNAHPGD
SCHEMBL6713101 0.74 MAOA (0.48) ALDH1A1KMT2ALMNAHPGDMAOA
SCHEMBL9835334 0.72 MAOA (0.47) ALDH1A1KMT2ALMNAHPGDMAOA
SCHEMBL11409437 0.72 ALDH1A1 (0.42) ALDH1A1HTTKMT2ALMNATP53
SCHEMBL19923522 0.72 SMO (0.53) KMT2AMAOASMOMEN1GAA
SCHEMBL5192164 0.72 MAOA (0.41) ALDH1A1HTTKMT2ALMNATSHR
SCHEMBL10541022 0.72 KMT2A (0.35) KMT2ALMNATSHRMAPK1MAOA
SCHEMBL19923639 0.68 MAOA (0.41) ALDH1A1HTTKMT2ALMNAMAPK1
SCHEMBL18937410 0.68 MAOA (0.38) ALDH1A1HTTKMT2ALMNAHPGD
SCHEMBL28410578 0.68 MAOA (0.38) ALDH1A1HTTKMT2ALMNAMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4602029-A CONTROLLING PLANT DISEASES CHEVRON RESEARCH COMPANY (US) 1986-07-22 US disclosed