Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | LOX | P28300 | 1/20 | 0.46 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.46 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713101 | 0.98 | MAOA (0.48) | MAOALOXLOXL3LOXL4LOXL2 | |
| SCHEMBL5192164 | 0.81 | MAOA (0.41) | MAOALOXLOXL3LOXL4LOXL2 | |
| SCHEMBL19923522 | 0.81 | SMO (0.53) | MAOAMEN1KMT2AGAACACNA1B | |
| SCHEMBL13340717 | 0.77 | MAOA (0.44) | MAOALOXLOXL3LOXL4LOXL2 | |
| SCHEMBL19923639 | 0.77 | MAOA (0.41) | MAOALOXLOXL3LOXL4LOXL2 | |
| SCHEMBL28410578 | 0.77 | MAOA (0.38) | MAOALOXLOXL3LOXL4LOXL2 | |
| SCHEMBL18937410 | 0.77 | MAOA (0.38) | MAOALOXLOXL3LOXL4LOXL2 | |
| SCHEMBL7173145 | 0.76 | LMNA (0.37) | MAOALOXLOXL3LOXL4LOXL2 | |
| SCHEMBL19923679 | 0.76 | LOX (0.39) | MAOALOXLOXL3LOXL4LOXL2 | |
| SCHEMBL10909817 | 0.76 | MAOA (0.37) | MAOALOXLOXL3LOXL4LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0216745-B1 | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED AMINOMETHYLPHOSPHONIC ACIDS | Monsanto Company (US) | 1991-10-16 | — | — | EP | disclosed |
| EP-0216744-B1 | THE COMPOUND 1,4-DIISOPROPYL-2,5-DIKETOPIPERAZINE | Monsanto Company (US) | 1991-08-14 | — | — | EP | disclosed |
| US-4804499-A | Process for the preparation of N-substituted aminomethylphosphonic acids | MONSANTO COMPANY (US) | 1989-02-14 | — | — | US | disclosed |
| US-4694081-A | FUNGICIDES | MONSANTO COMPANY (US) | 1987-09-15 | — | — | US | disclosed |
| US-4694082-A | CHEMICAL INTERMEDIATE FOR HERBICIDE | MONSANTO COMPANY (US) | 1987-09-15 | — | — | US | disclosed |
| EP-0216744-A2 | The compound 1,4-diisopropyl-2,5-diketopiperazine | Monsanto Company (US) | 1987-04-01 | — | — | EP | disclosed |
| EP-0216746-A2 | Process to prepare 2,5-diketopiperazines | Monsanto Company (US) | 1987-04-01 | — | — | EP | disclosed |
| EP-0216745-A1 | Process for the preparation of N-substituted aminomethylphosphonic acids | Monsanto Company (US) | 1987-04-01 | — | — | EP | disclosed |