Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10824828 | 0.79 | HTT (0.65) | HTTALDH1A1HPGDALOX12L3MBTL1 | |
| SCHEMBL28825258 | 0.77 | HTT (0.55) | HTTALDH1A1HPGDMCHR1L3MBTL1 | |
| SCHEMBL11700305 | 0.75 | ALDH1A1 (0.60) | HTTALDH1A1HPGDMCHR1ALOX12 | |
| SCHEMBL29152361 | 0.74 | ALDH1A1 (0.68) | HTTALDH1A1HPGDMCHR1ALOX12 | |
| SCHEMBL752826 | 0.72 | HTT (0.66) | HTTALDH1A1HPGDALOX12L3MBTL1 | |
| SCHEMBL29119860 | 0.72 | CYP3A4 (0.58) | HTTALDH1A1HPGDMCHR1ALOX12 | |
| SCHEMBL28158483 | 0.71 | ALDH1A1 (0.55) | HTTALDH1A1HPGDMCHR1ALOX12 | |
| SCHEMBL25936994 | 0.71 | HTT (0.55) | HTTALDH1A1HPGDALOX12L3MBTL1 | |
| SCHEMBL29738013 | 0.70 | AKR1B1 (0.52) | HPGDALOX12MEN1KMT2AGAA | |
| SCHEMBL6456130 | 0.70 | AKR1B1 (0.52) | HPGDALOX12MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4621123-A | Phosphinylmethyl polypenols and polyglycidyl ethers thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-11-04 | — | — | US | disclosed |