Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825321 | 0.88 | HTT (0.67) | HTTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL10910759 | 0.77 | HTT (0.77) | HTTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL10824828 | 0.76 | HTT (0.65) | HTTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL30956065 | 0.75 | KMT2A (0.43) | HTTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL29119880 | 0.74 | MEN1 (0.58) | HTTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL26090556 | 0.74 | NPSR1 (0.53) | MEN1KMT2AGAAALDH1A1HPGD | |
| SCHEMBL5167762 | 0.73 | ALDH1A1 (0.59) | MEN1KMT2AGAAALDH1A1HPGD | |
| SCHEMBL14076377 | 0.73 | RXRA (0.54) | MEN1KMT2AGAAALDH1A1HPGD | |
| SCHEMBL51349 | 0.71 | ALDH1A1 (0.61) | MEN1KMT2AGAAALDH1A1HPGD | |
| SCHEMBL29152361 | 0.71 | ALDH1A1 (0.68) | HTTMEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114933562-B | Efficient preparation method of chloroquine based on (2-hydroxybenzyl) disubstituted phosphine oxide catalysis | 华东理工大学 | 2024-07-23 | — | — | CN | disclosed |
| CN-114933562-A | Efficient preparation method of chloroquine based on catalysis of (2-hydroxybenzyl) disubstituted phosphine oxide | 华东理工大学 | 2022-08-23 | — | — | CN | disclosed |