Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7247250 | 0.90 | ALDH1A1 (0.42) | TRPV1CCR5KDM4EALDH1A1TSHR | |
| SCHEMBL11400542 | 0.85 | ALDH1A1 (0.49) | KDM4EALDH1A1ALOX15LMNACYP1A2 | |
| SCHEMBL11400920 | 0.85 | ALDH1A1 (0.49) | KDM4EALDH1A1ALOX15LMNACYP1A2 | |
| SCHEMBL10777783 | 0.80 | TRPV1 (0.41) | TRPV1CCR5KDM4EALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL11446968 | 0.78 | ALOX15 (0.56) | TRPV1CCR5KDM4EALDH1A1TSHR | |
| SCHEMBL9776124 | 0.76 | SMN1; SMN2 (0.47) | TRPV1KDM4EALDH1A1TSHRALOX15 | |
| SCHEMBL9776114 | 0.76 | SMN1; SMN2 (0.47) | TRPV1KDM4EALDH1A1TSHRALOX15 | |
| SCHEMBL11659308 | 0.76 | ITGB3 (0.49) | KDM4EALDH1A1RAB9AALOX15LMNA | |
| SCHEMBL22033119 | 0.75 | BLM (0.56) | KDM4EALDH1A1TSHRALOX15LMNA | |
| SCHEMBL6718744 | 0.75 | ALDH1A1 (0.56) | KDM4EALDH1A1GAAALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585892-A | Process for the enantioselective production of α-alkylated, acyclic α-aminocarboxylic acids | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |