Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 6/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110538 | 0.89 | ALDH1A1 (0.66) | ALDH1A1POLBRAD52HTR1ADRD2 | |
| SCHEMBL10832942 | 0.82 | ABCB1 (0.48) | ALDH1A1HTR1ADRD2DRD4MAPT | |
| SCHEMBL10910913 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HTR1ADRD2DRD4DRD3 | |
| SCHEMBL9285920 | 0.81 | HTR1A (0.61) | ALDH1A1POLBRAD52HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL6842632 | 0.80 | HTR1A (0.60) | ALDH1A1POLBRAD52HTR1ADRD2 | |
| SCHEMBL11759007 | 0.78 | ALDH1A1 (0.87) | ALDH1A1POLBHTR1ADRD2L3MBTL1 | |
| SCHEMBL10911340 | 0.78 | ALDH1A1 (0.62) | ALDH1A1POLBHTR1ADRD2L3MBTL1 | |
| SCHEMBL11856025 | 0.77 | HTR1A (0.52) | ALDH1A1POLBHTR1ADRD2DRD4 | |
| SCHEMBL8957751 | 0.77 | DRD2 (0.58) | ALDH1A1POLBHTR1ADRD2DRD3 | |
| Fluanisone SCHEMBL145054 | 0.76 | ALDH1A1 (1.00) | ALDH1A1POLBHTR1ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104614-B1 | PHENYLPIPERAZINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1986-12-30 | — | — | EP | claimed |
| EP-0104614-B1 | PHENYLPIPERAZINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1986-12-30 | — | — | EP | disclosed |