Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | BCHE | P06276 | 7/20 | 0.43 |
| ▸ | ACHE | P22303 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912182 | 0.97 | BCHE (0.44) | MAOBBCHEACHEAPP | |
| SCHEMBL10913068 | 0.93 | BCHE (0.46) | MAOBBCHEACHEAPP | |
| SCHEMBL10912465 | 0.91 | MAOB (0.43) | MAOBBCHEACHEMEN1NPC1 | |
| SCHEMBL10909868 | 0.90 | ALDH1A1 (0.46) | MAOBMEN1NPC1RAB9AKMT2A | |
| Dimethylamine SCHEMBL10913743 | 0.85 | RAB9A (0.41) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| Dimethylamine SCHEMBL10909871 | 0.84 | PDE10A (0.41) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL10909846 | 0.84 | RAB9A (0.36) | MAOBBCHEACHEMEN1NPC1 | |
| SCHEMBL10951254 | 0.84 | MAOB (0.47) | MAOBBCHEACHEMEN1NPC1 | |
| Diethylamine SCHEMBL10909850 | 0.84 | RAB9A (0.40) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL10914068 | 0.83 | PABPC1 (0.45) | MEN1NPC1RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |