Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911697 | 0.94 | MEN1 (0.45) | MEN1HTTKMT2AL3MBTL1CYP2D6 | |
| SCHEMBL10909998 | 0.88 | ADRB2 (0.46) | CYP2D6POLBADRB2ADRB1ADRB3 | |
| SCHEMBL10911546 | 0.86 | POLB (0.41) | MEN1HTTKMT2APOLBCA2 | |
| SCHEMBL10909686 | 0.84 | KMT2A (0.45) | MEN1HTTKMT2AL3MBTL1CYP2D6 | |
| SCHEMBL10913825 | 0.82 | ADRB2 (0.47) | CYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL10912183 | 0.82 | ADRB2 (0.47) | MEN1KMT2AL3MBTL1ADRB2ADRB1 | |
| SCHEMBL10912028 | 0.80 | ATM (0.39) | KMT2APOLBCA2ADRB2ADRB1 | |
| SCHEMBL10910014 | 0.79 | POLB (0.43) | MEN1HTTKMT2AL3MBTL1POLB | |
| SCHEMBL10913454 | 0.79 | L3MBTL1 (0.55) | MEN1KMT2AL3MBTL1ALDH1A1ADRB2 | |
| Dimethylamine SCHEMBL10912051 | 0.78 | RPS6KA2 (0.49) | MEN1HTTKMT2AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |